Direct effects of Prostaglandins (PGs) on Na transport of rabbit cortical collecting tubules perfused in vitro
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چکیده
منابع مشابه
Bicarbonate secretion by rabbit cortical collecting tubules in vitro.
We previously reported that rabbit renal cortical collecting tubules can secrete bicarbonate in vitro (i.e., there can be net transport from bath to lumen, causing the concentration in the lumen to increase). Net bicarbonate secretion was observed most often when rabbits had been pretreated with NaHCO(3) and were excreting alkaline urine before being killed for experiments. The purpose of the p...
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We examined effects of acetylcholine (ACh) on the electrical parameters and intracellular Ca2+ concentration ([Ca2+]i) in the isolated rabbit cortical collecting duct (CCD) perfused in vitro using the conventional microelectrode technique and microscopic fluorescence spectrophotometry. ACh (10(-8) to 10(-5) M) in the bath caused a positive deflection of the transepithelial voltage (VT) and an i...
متن کاملUltrastructural Studies of Vasopressin Effect on Isolated Perfused Renal Collecting Tubules of the Rabbit
Isolated cortical collecting tubules from rabbit kidney were studied during perfusion with solutions made either isotonic or hypotonic to the external bathing medium. Examination of living tubules revealed a reversible increase in thickness of the cellular layer, prominence of lateral cell membranes, and formation of intracellular vacuoles during periods of vasopressin-induced osmotic water tra...
متن کاملOsmosis in Cortical Collecting Tubules
This paper reports a theoretical analysis of osmotic transients and an experimental evaluation both of rapid time resolution of lumen to bath osmosis and of bidirectional steady-state osmosis in isolated rabbit cortical collecting tubules exposed to antidiuretic hormone (ADH). For the case of a membrane in series with unstirred layers, there may be considerable differences between initial and s...
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ژورنال
عنوان ژورنال: Japanese Journal of Pharmacology
سال: 1977
ISSN: 0021-5198
DOI: 10.1016/s0021-5198(19)66579-0